In 1996, Dr. W. Wayne Lautt—Professor Emeritus, Pharmacology and Therapeutics at the University of Manitoba—announced his remarkable discovery of a previously unidentified hormone: hepatic insulin-sensitizing substance (HISS).

This hormone, produced by the liver, is understood to be the missing link in science’s complete understanding of metabolic dysfunction, nutrient partitioning, and type 2 diabetes.

Research to verify the findings has continued ever since. SciMar Ltd. was founded in 2009 to advance Dr. Lautt’s pioneering medical research as he and his team work to unveil HISS as the foundation of a new paradigm in the prevention, detection, treatment, and ultimate reversal of type 2 diabetes.

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Makers of

A revolutionary daily supplement designed to support your metabolism, immunity, and mood balance

Based on the Dr. Lautt’s research into metabolic health and type 2 diabetes, SciMar has designed a powerful supplement to promote well-being.

SciMar NuPa Daily is currently available for sale in the United States and will be available for sale in Canada in the fall of 2021.

Learn more at

Convenors of the

Working together to restore human health

The Wellness Transformation Network is a community outreach and research initiative designed to promote healthy living and learn more about what lifestyle interventions have the greatest impact on metabolic health—all through the lens of SciMar’s research into HISS.

Current partners include a medically certified fitness facility, a diabetes education centre, private companies with workplace wellness programs, and Indigenous communities in Canada. Learn more at

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